Recent References

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53. C. Deng, M. Moinat, L. Curtis, A. Nadakal, F. Preitner, O. Boss, F. Assimacopoulos-Jeannet, J. Seydoux, J.-P. Giacobino (1997) Effects of β-adrenoceptor subtype stimulation on obese gene messenger ribonucleic acid and on leptin secretion in mouse brown adipocytes differentiated in culture. Endocrinology. 138, 548-552
74. P. Schrauwen, M.K.C. Hesselink, I. Vaartjes, E.Kornips, W.H. Saris, J.-P. Giacobino, A.-P. Russell (2002) Effect of acute exercise on uncoupling protein 3 is a fat metabolism-mediated effect. Am J Physiol Endocrinol Metab. 282, E11-17
103. S. Cinti, G. Barbatelli, I. Murano, L. Madsen, Q. Hao, M. Jimenez, K. Kristiansen, J.-P. Giacobino, R. De Matteis (2010) The emergence of cold-induced brown adipocytes in mouse white fat depots is predominantly determined by white to brown adipocyte transdifferentiation. Am J Physiol Endocrinol Metab. 298, E1244-53
K. J.-P. Giacobino (2002) Uncoupling proteins, leptin and obesity, an updated review. Ann N Y Acad Sci. 967, 398-402
45. L. Casteilla, P. Muzzin, J.-P. Revelli, D. Riquier, J.-P. Giacobino (1994) Expression of β1- and β3-adrenergic-receptor messages and adenylate cyclase b-adrenergic response in bovine perirenal adipose tissue during its transformation from brown into white fat. Biochem J. 297, 93-97
43. J.-P. Revelli, P. Muzzin, J.-P. Giacobino (1992) Modulation in vivo of β-adrenergic-receptor subtypes in rat brown adipose tissue by the thermogenic agonist Ro 16-8714. Biochem J. 286, 743-746
I. J.-P. Giacobino (2001) Uncoupling protein-3 biological activity. Biochem Soc Trans. 29, 774-778
72. M. Jimenez, R.A. Simonyan, R. Ceddia, J.-P. Giacobino, P. Muzzin, V. Skulachev (2001) Cold-induced changes in the energy coupling and the UCP3 level in rodent skeletal muscles. Biochim Biophys Acta. 1505, 271-279
50. C. Deng, A. Paoloni, F. Kühne, O. Boss, J.-P. Revelli, M. Moinat, M.A. Cawthorne, P. Muzzin, J.-P. Giacobino (1996) Respective degree of expression of β1-, β2- and β3-adrenoceptors in human brown and white adipose tissues. Br J Pharmacol. 118, 929-934
64. F. Preitner, P. Muzzin, J.-P. Revelli, J. Seydoux, J. Galtsky, M. Berlan, M. Lafontan, J.-P. Giacobino (1998) Metabolic response to various β3-adrenoceptor agonists in β3-adrenoceptor knockout mice : Evidence for a new β-adrenergic receptor in brown adipose tissue. Br J Pharmacol. 124, 1684-1688
69. J. Oostendorp, F. Preitner, J. Moffat, M. Jimenez, J.-P. Giacobino, P. Molenaar, A.J. Kaumann (2000) Contribution of β-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild type and β3-adrenoceptor knockout mice. Br J Pharmaol. 130, 747-758
91. K. Brixius, W. Bloch, C. Ziskoven, B. Bölck, A. Napp, C. Pott, D. Steinritz, M. Jimenez, K. Addicks, J.-P. Giacobino, R.H. Schwinger (2006) β3-adrenergic eNOS stimulation in left ventricular murine myocardium. Can J Physiol Pharmacol. 84, 1051-1060
49. J. Seydoux, P. Muzzin, M. Moinat, W. Pralong, L. Girardier, J.-P. Giacobino (1996) Adrenoceptor heterogeneity in human white adipocytes differentiated in culture as assessed by cytosolic free calcium measurements. Cell Signal. 8, 117-122
99. M.Crisan, S. Yap, L. Casteilla, C.W. Chen, M. Corselli, T.S Park, G. Andriolo, B. Sun, B. Zheng, L. Zhang, C. Norotte, P.N. Teng, J. Traas, R. Schugar, B.M. Deasy, S. Badylak, H.J. Bühring, J.-P. Giacobino, L. Lazzari, J. Huard, B. Péault (2008) A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs. Cell Stem Cell . 3, 301-313
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O. M. Crisan, J. Huard, B. Zheng, B. Sun, S. Yap, A. Logar, J.-P. Giacobino, L. Casteilla, B. Péault (2008) Purification and culture of human blood vessel-associated progenitor cells. Curr Protoc Stem Cell Biol. Chapter 2:Unit 2B.2.1-2B.2.13.
51. R. Bruskiewich, T. Everson, L. Ma, L. Chan, M. Schertzer, J.-P. Giacobino, P. Muzzin, S. Woods (1996) Analysis of CA repeat polymorphisms places three human gene loci on the 8p linkage map. Cytogenet Cell Genet. 73, 331-333
62. I. Cusin, K.E. Zakrzewska, O. Boss, P. Muzzin, J.-P. Giacobino, D. Ricquier, B. Jeanrenaud, F. Roner-Jeanrenaud (1998) Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins. Diabetes . 47, 1014-1019
83. A.-P. Russell, J. Feilchenfeldt, S. Schreiber, M. Praz, A.Crettenand, C. Gobelet, C.A. Meier, D.R. Bell, A. Kralli, J.-P. Giacobino, O. Deriaz (2003) Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-γ coactivator-1 and peroxisome proliferator-activated receptor-α in skeletal muscle. Diabetes. 52, 2874-2881
95. G. Gastaldi, A.-P. Russell, A. Golay, J.-P. Giacobino, F. Habicht, V. Barthassat, P. Muzzin, E. Bobbioni-Harsch (2007) Upregulation of peroxisome proliferator-activated receptor γ coactivator gene (PGC-1α) during weight loss is related to insulin sensitivity but not to energy expenditure. Diabetologia. 50, 2348-2355
52. E. Kuto, J.-P. Giacobino (1996) Interaction of nuclear factors with the cAMP response elements of the human β3-adrenoceptor gene. Endocrine. 5, 265-274
102. P. Flandin, L. Lehr, C. Asensio, J.-P. Giacobino, F. Rohner-Jeanrenaud, P. Muzzin, M. Jimenez (2009) Uncoupling protein-3 as a molecular determinant of the action of 3,5,3'-triiodothyronine on energy metabolism. Endocrine. 36, 246-254
98. E. Somm, V.M. Schwitzgebel, D.M. Vauthay, E.J. Camm, C.Y. Chen, J.-P. Giacobino, S.V. Sizonenko, M.L. Aubert, P.S. Hüppi (2008) Prenatal nicotine exposure alters early pancreatic islet and adipose tissue development with consequences on the control of body weight and glucose metabolism later in life. Endocrinology. 149, 6289-99
71. R. Ceddia, W.N. Wlliam Jr, F.B. Lima, P. Flandin, R. Curi, J.-P. Giacobino (2000) Leptin stimulates uncoupling protein-2 mRNA expression and Krebs cycle activity and inhibits lipid synthesis in isolated rat white adipocytes. Eur J Biochem. 267, 5952-5958
77. M. Jimenez, C. Yvon, L. Lehr, B. Léger, P. Keller, A.-P. Russell, F. Kühne, P. Flandin, J.-P. Giacobino, P. Muzzin (2002) Expression of uncoupling protein-3 in subsarcolemmal and intermyofibrillar mitochondria of various mouse muscle types and its modulation by fasting. Eur J Biochem. 269, 2878-2884
79. M. Jimenez, G. Barbatelli, R. Allevi, S. Cinti, J. Seydoux, J.-P. Giacobino, P. Muzzin, F. Preitner (2003) β3-adrenoceptor knockout in C57BL/6J mice depresses the occurrence of brown adipocytes in white fat. Eur J Biochem. 270, 699-705
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80. A.-P. Russell, G. Wadley, M.K.C. Hesselink, G. Schaart, S. Lo, B. Léger, A. Garnham, E. Kornips, D. Cameron-Smith, J.-P. Giacobino, P. Muzzin, R. Snow, P. Schrauwen (2003) UCP3 protein expression is lower in type I, IIa and IIx muscle fiber types of endurance-trained compared to untrained subjects. Eur J Phyiol. 445, 563-569
60. O. Boss, S. Samec, D. Desplanches, M.H. Mayet, J. Seydoux, P. Muzzin, J.-P. Giacobino (1998) Effect of endurance training on the expression of the uncoupling proteins 1, 2 and 3 in rat. FASEB J. 12, 335-339
48. M. Moinat, C. Deng, P. Muzzin, F. Assimacopoulos-Jeannet, J. Seydoux, A.G. Dulloo, J.-P. Giacobino (1995) Modulation of obese gene expression in rat brown and white adipose tissues. FEBS Lett. 373, 131-134
54. O. Boss, S. Samec, A. Paoloni, C. Rossier, A. Dulloo, J. Seydoux, P. Muzzin, J.-P. Giacobino (1997) Uncoupling protein-3 : a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett. 408, 39-42
55. O. Boss, S. Samec, A. Dulloo, J. Seydoux, P. Muzzin, J.-P. Giacobino (1997) Tissue-dependent upregulation of rat uncoupling protein-2 expression in response to fasting or cold. FEBS Lett. 412, 111-114
66. H. Kageyama, A. Suga, M. Kashiba, J. Oka, T. Osaka, T. Hirano, K. Nemoto, Y. Namba, D. Ricquier, J.-P. Giacobino, S. Inoue (1998) Increased uncoupling protein-2 and -3 gene expressions in skeletal muscle of STZ-induced diabetic rats. FEBS Lett . 440, 450-453
41. P. Muzzin, J.-P. Revelli, J.-P. Giacobino, C.M. Fraser (1992) Radioligand binding studies of the atypical β3-adrenergic receptor in rat brown adipose tissue using [3H]CGP 12177. FEBS Lett. 298, 162-164
67. A. Lanni, L. Beneduce, A. Lombardi, M. Moreno, O. Boss, P. Muzzin, J.-P. Giacobino, F.Goglia (1999) Expression of uncoupling protein-3 and mitochondrial activity in the transition from hypothyroid to hyperthyroid state in rat skeletal muscle. FEBS Lett. 444, 250-254
78. M. Jimenez, B. Léger, K. Canola, L. Lehr, P. Arboit, J. Seydoux, A.-P. Russell, J.-P. Giacobino, P. Muzzin, F. Preitner (2002) β123-adrenoceptor knockout mice are obese and cold-sensitive but have normal lipolytic responses to fasting. FEBS Lett. 530, 37-40
82. A.-P. Russell, G. Gastaldi, E. Bobbioni-Harsch, P. Arboit, C. Gobelet, O.Deriaz, A.Golay, J.L. Witzum, J.-P. Giacobino (2003) Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: a case of good vs. bad lipids? FEBS Lett. 551, 104-106
85. L. Lehr, F. Kühne, P. Arboit, J.-P. Giacobino, F.Poulin, P. Muzzin, M. Jimenez (2004) Control of 4E-BP1 expression in mouse brown adipose tissue by the β3-adrenoceptor. FEBS Lett. 576, 179-182
90. L. Lehr, K. Canola, C. Asensio, M. Jimenez, F. Kühne, J.-P. Giacobino, P. Muzzin (2006) The control of UCP1 is dissociated from that of PGC-1α or of mitochondriogenesis as revealed by a study using β-less mouse brown adipocytes in culture. FEBS Lett. 580, 4661-4666
59. O. Boss, J.-P. Giacobino, P. Muzzin (1998) Genomic structure of the uncoupling protein-3 (UCP3) and its assignment to chromosome 11q13. Genomics . 47, 311-313
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N. M. Crisan, B. Zheng, E. Zambidis, S. Yap, M. Tavian, B. Sun, J.-P. Giacobino, L. Casteilla, J.Huard, B. Péault (2007) Blood vessels as a source of progenitor cells in human embryonic and adult life. In: Stem Cells and their Potential for Clinical Application. Chapter II. N.M. Bilko et al. Eds.. 137-147
65. J.F. Surmley, M.J. Voirol, F. Assimacopoulos-Jeanet, J.-P. Giacobino, E. Jéquier, R.C. Gaillard, L. Tappy (1998) Stimulation by leptin of 3H GDP binding to brown adipose tissue of fasted but not fed rats. Int J Obes. 22, 923-926
70. A.G. Comuzzie, L. Almasy, S.A. Cole, O. Boss, J.-P. Giacobino, P. Muzzin, M.P. Stern, J.W. MacCluer, J. Blangero, J.E. Hixson (2000) Linkage exclusion analysis of the chromosome 11 region containing UCP2 and UCP3 with obesity-related phenotypes in Mexican Americans. Int J Obes. 24, 1065-1068
92. D. Mainieri, J.-P. Montani, J. Seydoux, J.-P. Giacobino, O. Boss, A.G. Dulloo (2007) β-adrenergic control of stearoyl-CoA desaturase 1 repression in relation to sympathoadrenal regulation of thermogenesis. Int J Obes. 31, 378-381
96. C.S. Asensio, D. Arsenijevic, L. Lehr, J.-P. Giacobino, P. Muzzin, F.Rohner-Jeanrenaud (2008) Effects of leptin on energy metabolism in β-less mice. Int J Obes. 32, 936-942
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100. L. Lehr, K. Canola, B. Léger, J.-P. Giacobino (2009) Differentiation and characterization in primary culture of white adipose tissue brown adipocyte-like cells. Int J Obes. 33, 680-686
105. A.-P. Russell, M. Crisan, B. Léger, M. Corselli, A.J. McAinch, P.E. O'Brien, D. Cameron-Smith, B. Péault, L. Casteilla, J.-P. Giacobino (2012) Brown adipocyte progenitor population is modified in obese and diabetic skeletal muscle. Int J Obes (Lond). 36 155-158
75. A.-P. Russell, G. Wadley, R. Snow, J.-P. Giacobino, P. Muzzin, A. Garnham, D. Cameron-Smith (2002) Slow component of VO2 kinetics: the effect of training status, fibre type, UCP3 mRNA and citrate synthase activity. Int J Obes Relat Metab Disord. 26, 157-164
76. C.M. Lanouette, Y.C. Chagnon, T. Rice, L. Pérusse, P. Muzzin, J.-P. Giacobino, J. Gagnon, J.H. Wilmore, A.S. Leon, J.S. Skinner, D.C. Rao, C. Bouchard (2002) Uncoupling protein 3 gene is associated with body composition changes with training in HERITAGE study. J Appl Physiol. 92, 111-1118
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57. O. Boss, S. Samec, F. Kühne, P. Bijlenga, F. Assimacopoulos-Jeannet , J.Seydoux, J.-P. Giacobino, P. Muzzin (1998) Uncoupling protein-3 expression in rodent skeletal muscle is modulated by food intake but not by changes in environmental temperature. J Biol Chem. 273, 5-8
40. P. Muzzin, J.-P. Revelli, F. Kühne, J.D. Gocayne, W.R. McCombie, J.C. Venter, J.-P. Giacobino, C.M. Fraser (1991) An adipose tissue-specific β-adrenergic receptor. Molecular cloning and down-regulation in obesity. J Biol Chem. 266, 24053-24058
42. V. Vivat, J. Cohen-Tannoudji, J.-P. Revelli, P. Muzzin, J.-P. Giacobino, J.-P.Maltier, C.Legrand (1992) Progesterone transcriptionally regulates the β2-adrenergic receptor gene in pregnant rat myometrium. J Biol Chem. 267, 7975-7978
86. A.-P. Russell, E. Somm, R. Debigare, O. Hartley, D. Richard, G. Gastaldi, A. Melotti, A. Michaud, J.-P. Giacobino, P. Muzzin, P. LeBlanc, F.Maltais (2004) COPD results in a reduction in UCP3 long mRNA and UCP3 protein content in types I and IIa skeletal muscle fibers. J Cardiopulm Rehabil. 24, 332-339
84. A.-P. Russell, P. Schrauwen, E. Somm, G. Gastaldi, M.K.C. Hesselink, G. Schaart, E. Kornips, S.K. Lo, D. Bufano, J.-P. Giacobino, P. Muzzin, M. Ceccon, C. Angelini, L. Vergani (2003) Decreased fatty acid beta-oxidation in riboflavin-responsive, multiple acylcoenzyme A dehydrogenase-deficient patients is associated with an increase in uncoupling protein-3. J Clin Endocrinol Metab. 88, 5921-5926
56. J.-P. Revelli, F. Preitner, Samec S., Muniesa P., Kuehne F., O. Boss, Vassali J.D., Dulloo A., Seydoux J., J.-P. Giacobino, Huarte J., Ody C. (1997) Targeted gene disruption reveals a leptin-independent role for the mouse β3-adrenoceptor in the regulation of body composition. J Clin Invest. 100, 1098-1106
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44. J.-P. Revelli, P. Muzzin, A. Paoloni, M. Moinat, J.-P. Giacobino (1993) Expression of the β3-adrenergic receptor in human white adipose tissue. J Mol Endocrinol. 10, 193-197
94. T. Matsuura, Y. Li, J.-P. Giacobino, F.H. Fu, J. Huard (2007) Skeletal muscle fiber type conversion during the repair of mouse soleus: potential implications for muscle healing after injury. J Orthop Res. 25, 1534-150
81. A.-P. Russell, E. Somm, M. Praz, A.Crettenand, O. Hartley, A. Melotti, J.-P. Giacobino, P. Muzzin, C. Gobelet, O. Deriaz (2003) UCP3 protein regulation in human skeletal muscle fibre types I, IIa and IIx is dependent on exercise intensity. J Physiol. 550, 855-861
63. O. Boss, E. Bobbioni-Harsch, F. Assimacopoulos-Jeannet, P. Muzzin, R. Munger, J.-P. Giacobino, A. Golay (1998) Uncoupling protein-3 expression in skeletal muscle and free fatty acids in obese humans. Lancet . 351, 1933
58. E. Kuto, O. Boss, F. Levasseur, J.-P. Giacobino (1998) Quantification of the full length leptin receptor (OB-Rb) in human brown and white adipose tissue. Life Sci. 62, 445-451
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47. S. Klaus, P. Muzzin, J.-P. Revelli, M.A. Cawthorn, J.-P. Giacobino, D. Ricquier (1995) Control of β3-adrenergic receptor gene expression in brown adipocytes in culture. Mol Cell Endocrinol. 109, 189-195
73. C.M. Lanouette, J.-P. Giacobino, L. Pérusse, M. Lacaille, C. Yvon, M. Chagnon, F. Kühne, C. Bouchard, P. Muzzin, Y.C. Chagnon (2001) Association between uncoupling protein 3 gene and obesity-related phenotypes in the Québec Family Study. Mol Med. 7, 433-441
46. P. Muzzin, O. Boss, N. Mathis, J.-P. Revelli, J.-P. Giacobino, K. Willcoks, G.T. Badman, B.C.C. Cantello, R.M. Hindley, M.A. Cawthorne (1994) Characterization of a highly specific new β3-adrenergic receptor radioligand: [3H]SB 206606. Mol Pharmacol. 46, 357-363
61. A.J. Kauman, F. Preitner, D. Sarsero, P. Molenaar, J.-P. Revelli, J.-P. Giacobino (1998) (-)-CGP 12177 causes cardiostimulation and binds to cardiac putative β4-adrenoceptors in both wild type and β3-adrenoceptor knockout mice. Mol Pharmacol . 53, 670-675
88. G. Tavernier, M. Jimenez, J.-P. Giacobino, N. Hulo, M. Lafontan, P. Muzzin, D.Langin (2005) Norepinephrine induces lipolysis in β123-adrenoceptor knockout mice. Mol Pharmacol. 68, 793-799
101. B. Léger, R. Senese, A.W. Al-Khodairy, O. Dériaz , Ch. Gobelet, J.-P. Giacobino, A.-P. Russell (2009) Atrogin-1, MuRF1, and FoXO, as well as phosphorylated GSK-3beta and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients. Muscle nerve. 40, 69-78
89. P. Keller, V. Compan, J. Bockaert, J.-P. Giacobino, Y. Charnay, C. Bouras, F. Assimacopoulos-Jeannet (2006) Characterization and localization of cocaine- and amphetamine-regulated transcript (CART) binding sites. Peptides. 27, 1328-1334
93. C. Ziskoven, S. Grafweg, B. Bölck, R.J. Wiesner, M. Jimenez, J.-P. Giacobino, W. Bloch, R.H. Schwinger, K. Brixius (2007) Increased Ca2+ sensitivity and protein expression of SERCA 2a in situations of chronic β3-adrenoceptor deficiency. Pflügers Arch. 453, 443-453
68. T. Grandi, P. Muzzin, J.-P. Giacobino, F. Sparatore (1999) Synthesis and pharmalogical investigation of new arylethanolamines as β3-adrenoceptor ligands. Pharm Pharmacol Comm. 5, 561-564
87. P. Keller, L. Lehr, J.-P. Giacobino, J.-P. Charnay, N. Giovannini, F. Assimacopoulos-Jeannet (2005) Cloning, ontogenesis, and localization of an atypical uncoupling protein 4 in Xenopus laevis. Physiol Genomics. 22, 339-345
104. S. Lee, S. Grafweg, T. Schneider, M. Jimenez, J.-P. Giacobino, A. Ghanem, K. Tiemann, W. Bloch, J. Müller-Ehmsen, R.H. Schwinger, K. Brixius (2010) Total β-adrenoceptor deficiency results in cardiac hypotrophy and negative inotropy. Physiol Res. 59 679-689
97. M. Crisan, L. Casteilla, L. Lehr, M. Carmona, A. Paoloni, S. Yap, B. Sun, B. Léger, A. Logar, L. Pénicaud, P. Schrauwen, D. Cameron-Smith, A.-P. Russell, B. Péault, J.-P. Giacobino (2008) A reservoir of brown adipocyte progenitors in human skeletal muscle. Stem Cells. 26, 2425-33
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